Azamethiphos

Common name: azamethiphos
IUPAC name: S-6-chloro-2, 3-dihydro-2-oxo-1, 3-oxazolo[4, 5-b]pyridin-3-ylmethyl O, O-dimethyl phosphorothioate; 6-chloro-3-dimethoxyphosphinoylthiomethyl-1, 3-oxazolo[4, 5-b]pyridin-2(3H)-one
Chemical Abstracts name: S-[(6-chloro-2-oxooxazolo[4, 5-b]pyridin-3(2H)-yl)methyl] O, O-dimethyl phosphorothioate
CAS RN: [35575-96-3]
EEC no.: 252-626-0

PHYSICAL CHEMISTRY
Composition: Tech. is >95%. Mol. wt.: 324.7; M.f.: C9H10ClN2O5PS; Form: Colourless crystals; (tech. is a beige to grey powder). M.p.: 89 ºC. V.p.: 0.0049 mPa (20 ºC). KOW: logP = 1.05; Henry: 1.45x10-6 Pa m3 mol-1 (calc.) S.g./density: 1.60 (20 ºC). Solubility: In water 1.1 g/l (pH 7, 20 ºC). In dichloromethane 610, benzene 130, methanol 100, n-octanol 5.8 (all in g/kg, 20 ºC). Stability: Unstable in acids and alkalis; DT50 (20 ºC) (calc.): 800 h (pH 5), 260 h (pH 7), 4.3 h (pH 9). F.p.: >150 °C (Marcusson, without stirring).

APPLICATIONS
Biochemistry: Cholinesterase inhibitor.
Mode of action: Insecticide with contact and stomach action. Gives rapid knockdown, and has good residual activity.
Uses: Control of flies and other insect pests in animal houses. Control of mosquitoes, tsetse flies, cockroaches, and other public hygiene pests.
Formulation types: AE; WP.